17β-Estradiol Protects Rat Annulus Fibrosus Cells Against Apoptosis via α(1) Integrin-Mediated Adhesion to Type I Collagen: An In-vitro Study

BACKGROUND: 17β-Estradiol (E2) has been reported to protect annulus fibrosus (AF) cells in vitro against interleukin-1β (IL-1β)-induced apoptosis in a concentration-dependent manner. However, its time-response effect remains unexplored. In addition, integrin α(2)/collagen II interaction has been rep...

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Bibliographic Details
Published in:Med Sci Monit
Main Authors: Zhao, Chun-Ming, Chen, Qian, Zhang, Wen-Jie, Huang, Ai-Bing, Zhang, Wei, Yang, Hui-Lin, Zhang, Zhi-Ming
Format: Artigo
Language:Inglês
Published: International Scientific Literature, Inc. 2016
Subjects:
Animal Study
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846184/
https://ncbi.nlm.nih.gov/pubmed/27108411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.897906
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