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High-glucose environment accelerates annulus fibrosus cell apoptosis by regulating endoplasmic reticulum stress

Diabetes mellitus (DM) is an important risk factor of intervertebral disc degeneration. However, how DM affects annulus fibrosus (AF) biology remains unclear. The present study was aimed to investigate the effects and mechanism of high glucose on AF cell biology. Rat AF cells were cultured in baseli...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Pang, Lianglong, Yang, Keshi, Zhang, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328627/
https://ncbi.nlm.nih.gov/pubmed/32515472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20200262
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