A Meta-Analysis of Retinoblastoma Copy Numbers Refines the List of Possible Driver Genes Involved in Tumor Progression

BACKGROUND: While RB1 loss initiates retinoblastoma development, additional somatic copy number alterations (SCNAs) can drive tumor progression. Although SCNAs have been identified with good concordance between studies at a cytoband resolution, accurate identification of single genes for all recurre...

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Pubblicato in:PLoS One
Autori principali: Kooi, Irsan E., Mol, Berber M., Massink, Maarten P. G., de Jong, Marcus C., de Graaf, Pim, van der Valk, Paul, Meijers-Heijboer, Hanne, Kaspers, Gertjan J. L., Moll, Annette C., te Riele, Hein, Cloos, Jacqueline, Dorsman, Josephine C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846005/
https://ncbi.nlm.nih.gov/pubmed/27115612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153323
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