Mitogenic signaling pathways in the liver of growth hormone (GH)-overexpressing mice during the growth period

Growth hormone (GH) is a pleiotropic hormone that triggers STATs, ERK1/2 and Akt signaling, related to cell growth and proliferation. Transgenic mice overexpressing GH present increased body size, with a disproportionate liver enlargement due to hypertrophy and hyperplasia of the hepatocytes. We had...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Cycle
Main Authors: Martinez, Carolina S., Piazza, Verónica G., González, Lorena, Fang, Yimin, Bartke, Andrzej, Turyn, Daniel, Miquet, Johanna G., Sotelo, Ana I.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845918/
https://ncbi.nlm.nih.gov/pubmed/27028000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1148844
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