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The human 64-kDa polyadenylylation factor contains a ribonucleoprotein-type RNA binding domain and unusual auxiliary motifs.

Cleavage stimulation factor is one of the multiple factors required for 3'-end cleavage of mammalian pre-mRNAs. We have shown previously that this factor is composed of three subunits with estimated molecular masses of 77, 64, and 50 kDa and that the 64-kDa subunit can be UV-crosslinked to RNA in a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Takagaki, Y, MacDonald, C C, Shenk, T, Manley, J L
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48459/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1741396/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.4.1403
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