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Differential requirement for IL-2 and IL-15 during bifurcated development of thymic regulatory T cells
The developmental pathways of regulatory T cells (T(reg)) generation in the thymus are not fully understood. Here, we reconstituted thymic development of Zap70 deficient thymocytes with a tetracycline inducible Zap70 transgene to allow temporal dissection of T(reg) development. We find that T(reg) d...
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| Veröffentlicht in: | J Immunol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4845883/ https://ncbi.nlm.nih.gov/pubmed/25348623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402144 |
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