Carregant...

Quantification of active mitochondrial permeability transition pores using GNX-4975 inhibitor titrations provides insights into molecular identity

Inhibition of the mitochondrial permeability transition pore (MPTP) by the novel inhibitor GNX-4975 was characterized. Titration of MPTP activity in de-energized rat liver mitochondria allowed determination of the number of GNX-4975-binding sites and their dissociation constant (K(i)). Binding sites...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Biochem J
Autors principals: Richardson, Andrew P., Halestrap, Andrew P.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845862/
https://ncbi.nlm.nih.gov/pubmed/26920024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160070
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!