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Detection of IFN-γ Secretion by T Cells Collected Before and After Successful Treatment of Early Lyme Disease

Background. Current serodiagnostics for Lyme disease lack sensitivity during early disease, and cannot determine treatment response. We evaluated an assay based on QuantiFERON technology utilizing peptide antigens derived from Borrelia burgdorferi to stimulate interferon-gamma (IFN-γ) release as an...

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Bibliografische gegevens
Gepubliceerd in:Clin Infect Dis
Hoofdauteurs: Callister, Steven M., Jobe, Dean A., Stuparic-Stancic, Aleksandra, Miyamasu, Misato, Boyle, Jeff, Dattwyler, Raymond J., Arnaboldi, Paul M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845790/
https://ncbi.nlm.nih.gov/pubmed/26936671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciw112
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