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Detection of IFN-γ Secretion by T Cells Collected Before and After Successful Treatment of Early Lyme Disease

Background. Current serodiagnostics for Lyme disease lack sensitivity during early disease, and cannot determine treatment response. We evaluated an assay based on QuantiFERON technology utilizing peptide antigens derived from Borrelia burgdorferi to stimulate interferon-gamma (IFN-γ) release as an...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Callister, Steven M., Jobe, Dean A., Stuparic-Stancic, Aleksandra, Miyamasu, Misato, Boyle, Jeff, Dattwyler, Raymond J., Arnaboldi, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845790/
https://ncbi.nlm.nih.gov/pubmed/26936671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciw112
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