Comparative Study of Different Combinational Mucoadhesive Formulations of Sumatriptan-Metoclopramide

Purpose: Sumatriptan succinate (Sum) is a Serotonin 5- HT1 receptor agonist, used in the treatment of migraine. It is absorbed rapidly but incompletely when taken orally and underwent first - pass metabolism, resulting in a low bioavailability of about 15%. The aim was to design mucoadhesive buccal...

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Bibliografiske detaljer
Udgivet i:Adv Pharm Bull
Main Authors: Jelvehgari, Mitra, Valizadeh, Hadi, Ziapour, Sanam, Rahmani, Mahdieh, Montazam, Seyed Hassan, Soltani, Saieede
Format: Artigo
Sprog:Inglês
Udgivet: Tabriz University of Medical Sciences 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845549/
https://ncbi.nlm.nih.gov/pubmed/27123427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2016.018
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