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Experimental Design to Predict Process Variables in the Microcrystals of Celecoxib for Dissolution Rate Enhancement Using Response Surface Methodology
Purpose: The purpose of the present investigation was to increase the solubility and dissolution rate of celecoxib (CLX) by preparing microcrystals of drug by solvent change precipitation. Methods: This procedure was optimized in order to obtain stable and homogeneous particles with a small particle...
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| Publicado no: | Adv Pharm Bull |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Tabriz University of Medical Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4517079/ https://ncbi.nlm.nih.gov/pubmed/26236663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2015.033 |
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