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Experimental Design to Predict Process Variables in the Microcrystals of Celecoxib for Dissolution Rate Enhancement Using Response Surface Methodology

Purpose: The purpose of the present investigation was to increase the solubility and dissolution rate of celecoxib (CLX) by preparing microcrystals of drug by solvent change precipitation. Methods: This procedure was optimized in order to obtain stable and homogeneous particles with a small particle...

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Detaylı Bibliyografya
Yayımlandı:Adv Pharm Bull
Asıl Yazarlar: Jelvehgari, Mitra, Valizadeh, Hadi, Montazam, Seyed Hassan, Abbaszadeh, Sanam
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Tabriz University of Medical Sciences 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517079/
https://ncbi.nlm.nih.gov/pubmed/26236663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2015.033
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