Tumor Necrosis Factor–Related Apoptosis‐Inducing Ligand (TRAIL) Promotes Angiogenesis and Ischemia‐Induced Neovascularization Via NADPH Oxidase 4 (NOX4) and Nitric Oxide–Dependent Mechanisms

BACKGROUND: Tumor necrosis factor–related apoptosis‐inducing ligand (TRAIL) has the ability to inhibit angiogenesis by inducing endothelial cell death, as well as being able to promote pro‐angiogenic activity in vitro. These seemingly opposite effects make its role in ischemic disease unclear. Using...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Di Bartolo, Belinda Ann, Cartland, Siân Peta, Prado‐Lourenco, Leonel, Griffith, Thomas Scott, Gentile, Carmine, Ravindran, Jayant, Azahri, Nor Saadah Muhammad, Thai, Thuan, Yeung, Amanda Wing Shee, Thomas, Shane Ross, Kavurma, Mary Meltem
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845240/
https://ncbi.nlm.nih.gov/pubmed/26572549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002527
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