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TRAIL Deficiency Contributes to Diabetic Nephropathy in Fat-Fed ApoE(-/-) Mice

BACKGROUND: We recently demonstrated that TNF-related apoptosis-inducing ligand (TRAIL) is protective of diet-induced diabetes in mice. While TRAIL has been implicated in chronic kidney disease, its role in vivo in diabetic nephropathy is not clear. The present study investigated the role of TRAIL i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cartland, Siân P., Erlich, Jonathan H., Kavurma, Mary M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965481/
https://ncbi.nlm.nih.gov/pubmed/24667560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092952
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