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The stress of coping with E2F loss

E2F transcription factors are key regulators of cellular proliferation, and altered E2F activity is a common feature of tumor cells. Thus, E2F targeting is being explored as a therapeutic strategy in cancer. Importantly, recent mouse knockout studies show that concomitant loss of E2f1/E2f2 activity...

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Détails bibliographiques
Publié dans:Mol Cell Oncol
Auteurs principaux: Iglesias-Ara, Ainhoa, Zubiaga, Ana M.
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845195/
https://ncbi.nlm.nih.gov/pubmed/27308555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1038423
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