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Diabetes and exocrine pancreatic insufficiency in E2F1/E2F2 double-mutant mice
E2F transcription factors are thought to be key regulators of cell growth control. Here we use mutant mouse strains to investigate the function of E2F1 and E2F2 in vivo. E2F1/E2F2 compound-mutant mice develop nonautoimmune insulin-deficient diabetes and exocrine pancreatic dysfunction characterized...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC406522/ https://ncbi.nlm.nih.gov/pubmed/15146237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200418879 |
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