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Involvement of USP24 in the DNA damage response

Deubiquitination has emerged as an important mechanism of regulating DNA repair pathways. We recently reported that USP24 is a novel p53 deubiquitinase that stabilizes p53 upon DNA damage. USP24 is upregulated by DNA damaging agents and plays an important role in maintaining genome stability.

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Oncol
Hauptverfasser: Zhang, Ling, Gong, Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845166/
https://ncbi.nlm.nih.gov/pubmed/27308530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1011888
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