Role of Indoxyl Sulfate as a Predisposing Factor for Atrial Fibrillation in Renal Dysfunction

BACKGROUND: Renal dysfunction is a major risk factor for atrial fibrillation (AF). The uremic toxin indoxyl sulfate may contribute to the progression of cardiac fibrosis and AF substrate in renal dysfunction. METHODS AND RESULTS: Male Sprague–Dawley rats were assigned randomly to the following group...

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Detalles Bibliográficos
Publicado en:J Am Heart Assoc
Main Authors: Aoki, Kohei, Teshima, Yasushi, Kondo, Hidekazu, Saito, Shotaro, Fukui, Akira, Fukunaga, Naoya, Nawata, Tomoko, Shimada, Tatsuo, Takahashi, Naohiko, Shibata, Hirotaka
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2015
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845145/
https://ncbi.nlm.nih.gov/pubmed/26452986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002023
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