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Hepatic microsomal metabolism of indole to indoxyl, a precursor of indoxyl sulfate
The aim of our study was to determine which microsomal cytochrome P450 isozyme(s) were responsible for the microsomal oxidation of indole to indoxyl, an important intermediate in the formation of the uremic toxin indoxyl sulfate. Indole was incubated together with an NADPH-generating system and rat...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2254176/ https://ncbi.nlm.nih.gov/pubmed/11808865 |
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