Inhibitor Recognition Specificity of MERS-CoV Papain-like Protease May Differ from That of SARS-CoV

[Image: see text] The Middle East Respiratory Syndrome coronavirus (MERS-CoV) papain-like protease (PLpro) blocking loop 2 (BL2) structure differs significantly from that of SARS-CoV PLpro, where it has been proven to play a crucial role in SARS-CoV PLpro inhibitor binding. Four SARS-CoV PLpro lead...

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Publicat a:ACS Chem Biol
Autors principals: Lee, Hyun, Lei, Hao, Santarsiero, Bernard D., Gatuz, Joseph L., Cao, Shuyi, Rice, Amy J., Patel, Kavankumar, Szypulinski, Michael Z., Ojeda, Isabel, Ghosh, Arun K., Johnson, Michael E.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2015
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845099/
https://ncbi.nlm.nih.gov/pubmed/25746232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500917m
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