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Target delivery of small interfering RNAs with vitamin E-coupled nanoparticles for treating hepatitis C

RNA interference (RNAi) represents a promising strategy for the treatment of HCV infection. However, the development of an effective system for in vivo delivery of small interfering RNA (siRNA) to target organ remains a formidable challenge. Here, we develop a unique nanoparticle platform (VE-DC) co...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Duan, Liang, Yan, Yan, Liu, Jingyi, Wang, Bo, Li, Pu, Hu, Qin, Chen, Weixian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845054/
https://ncbi.nlm.nih.gov/pubmed/27113197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24867
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