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Combining measurements to estimate properties and characterization extent of complex biochemical mixtures; applications to Heparan Sulfate

Complex mixtures of molecular species, such as glycoproteins and glycosaminoglycans, have important biological and therapeutic functions. Characterization of these mixtures with analytical chemistry measurements is an important step when developing generic drugs such as biosimilars. Recent developme...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pradines, Joël R., Beccati, Daniela, Lech, Miroslaw, Ozug, Jennifer, Farutin, Victor, Huang, Yongqing, Gunay, Nur Sibel, Capila, Ishan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845011/
https://ncbi.nlm.nih.gov/pubmed/27112127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24829
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