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IL-13 mediates collagen deposition via STAT6 and microRNA-135b: a role for epigenetics
Systemic sclerosis is an autoimmune connective tissue disease in which T cells play a prominent role. We and others have previously demonstrated a role for T cell-derived IL-13 in mediating the induction of collagen in dermal fibroblasts and that blockade with IL-13 antibodies attenuates this increa...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4844987/ https://ncbi.nlm.nih.gov/pubmed/27113293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25066 |
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