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Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model

The transforming growth factor-β (TGF-β) family is known to play critical roles in cancer progression. While the dual role of TGF-β is well described, the function of bone morphogenetic proteins (BMPs) is unclear. In this study, we established the involvement of Smad6, a BMP-specific inhibitory Smad...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: de Boeck, Miriam, Cui, Chao, Mulder, Aat A, Jost, Carolina R, Ikeno, Souichi, ten Dijke, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844967/
https://ncbi.nlm.nih.gov/pubmed/27113436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24968
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