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Design of a RANK-Mimetic Peptide Inhibitor of Osteoclastogenesis with Enhanced RANKL-Binding Affinity

The receptor activator of nuclear factor κB (RANK) and its ligand RANKL are key regulators of osteoclastogenesis and well-recognized targets in developing treatments for bone disorders associated with excessive bone resorption, such as osteoporosis. Our previous work on the structure of the RANK-RAN...

詳細記述

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書誌詳細
出版年:Mol Cells
主要な著者: Hur, Jeonghwan, Ghosh, Ambarnil, Kim, Kabsun, Ta, Hai Minh, Kim, Hyunju, Kim, Nacksung, Hwang, Hye-Yeon, Kim, Kyeong Kyu
フォーマット: Artigo
言語:Inglês
出版事項: Korean Society for Molecular and Cellular Biology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844938/
https://ncbi.nlm.nih.gov/pubmed/26923188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2016.2286
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