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Wntless spatially regulates bone development through β-catenin-dependent and independent mechanisms
BACKGROUND: Canonical and noncanonical Wnt signaling pathways both play pivotal roles in bone development. Wntless/GPR177 is a chaperone protein that is required for secretion of all Wnt ligands. We previously showed that deletion of Wntless within mature osteoblasts severely impaired postnatal bone...
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| Veröffentlicht in: | Dev Dyn |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4844555/ https://ncbi.nlm.nih.gov/pubmed/26249818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24316 |
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