Wntless spatially regulates bone development through β-catenin-dependent and independent mechanisms

BACKGROUND: Canonical and noncanonical Wnt signaling pathways both play pivotal roles in bone development. Wntless/GPR177 is a chaperone protein that is required for secretion of all Wnt ligands. We previously showed that deletion of Wntless within mature osteoblasts severely impaired postnatal bone...

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Bibliografiske detaljer
Udgivet i:Dev Dyn
Main Authors: Zhong, Zhendong A., Zahatnansky, Juraj, Snider, John, Van Wieren, Emily, Diegel, Cassandra R., Williams, Bart O.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844555/
https://ncbi.nlm.nih.gov/pubmed/26249818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24316
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