Abnormal IGF-Binding Protein Profile in the Bone Marrow of Multiple Myeloma Patients

Insulin-like growth factor (IGF) signalling plays a key role in homing, progression, and treatment resistance in multiple myeloma (MM). In the extracellular environment, the majority of IGF molecules are bound to one of six IGF-binding proteins (IGFBP1-6), leaving a minor fraction of total IGF free...

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Udgivet i:PLoS One
Main Authors: Bieghs, Liesbeth, Brohus, Malene, Kristensen, Ida B., Abildgaard, Niels, Bøgsted, Martin, Johnsen, Hans E., Conover, Cheryl A., De Bruyne, Elke, Vanderkerken, Karin, Overgaard, Michael T., Nyegaard, Mette
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844248/
https://ncbi.nlm.nih.gov/pubmed/27111220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154256
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