Assessing bioequivalence of generic modified-release antiepileptic drugs

OBJECTIVES: The purpose of this study was to determine how closely generic modified-release antiepileptic drugs (MR-AEDs) resemble reference (brand) formulations by comparing peak concentrations (Cmax), total absorption (area under the curve [AUC]), time to Cmax (Tmax), intersubject variability, and...

Full description

Saved in:
Bibliographic Details
Published in:Neurology
Main Authors: Johnson, Emily L., Chang, Yi-Ting, Davit, Barbara, Gidal, Barry E., Krauss, Gregory L.
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844239/
https://ncbi.nlm.nih.gov/pubmed/27016518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002607
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items