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Assessing bioequivalence of generic modified-release antiepileptic drugs

OBJECTIVES: The purpose of this study was to determine how closely generic modified-release antiepileptic drugs (MR-AEDs) resemble reference (brand) formulations by comparing peak concentrations (Cmax), total absorption (area under the curve [AUC]), time to Cmax (Tmax), intersubject variability, and...

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Bibliografiska uppgifter
I publikationen:Neurology
Huvudupphovsmän: Johnson, Emily L., Chang, Yi-Ting, Davit, Barbara, Gidal, Barry E., Krauss, Gregory L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Lippincott Williams & Wilkins 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844239/
https://ncbi.nlm.nih.gov/pubmed/27016518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002607
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