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A lincRNA connected to cell mortality and epigenetically-silenced in most common human cancers

Immortality is an essential characteristic of human carcinoma cells. We recently developed an efficient, reproducible method that immortalizes human mammary epithelial cells (HMEC) in the absence of gross genomic changes by targeting 2 critical senescence barriers. Consistent transcriptomic changes...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Vrba, Lukas, Garbe, James C, Stampfer, Martha R, Futscher, Bernard W
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844203/
https://ncbi.nlm.nih.gov/pubmed/26646903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1106673
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