A lincRNA connected to cell mortality and epigenetically-silenced in most common human cancers

Immortality is an essential characteristic of human carcinoma cells. We recently developed an efficient, reproducible method that immortalizes human mammary epithelial cells (HMEC) in the absence of gross genomic changes by targeting 2 critical senescence barriers. Consistent transcriptomic changes...

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Detalles Bibliográficos
Publicado en:Epigenetics
Autores principales: Vrba, Lukas, Garbe, James C, Stampfer, Martha R, Futscher, Bernard W
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844203/
https://ncbi.nlm.nih.gov/pubmed/26646903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1106673
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