Site-specific Proteasome Phosphorylation Controls Cell Proliferation and Tumorigenesis

Despite the fundamental importance of proteasomal degradation in cells, little is known about whether and how the 26S proteasome itself is regulated in coordination with various physiological processes. Here we show that the proteasome is dynamically phosphorylated during cell cycle at Thr25 of the...

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Bibliographic Details
Published in:Nat Cell Biol
Main Authors: Guo, Xing, Wang, Xiaorong, Wang, Zhiping, Banerjee, Sourav, Yang, Jing, Huang, Lan, Dixon, Jack E.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844191/
https://ncbi.nlm.nih.gov/pubmed/26655835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3289
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