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Single-Cell Migration in Complex Microenvironments: Mechanics and Signaling Dynamics

Cells are highly dynamic and mechanical automata powered by molecular motors that respond to external cues. Intracellular signaling pathways, either chemical or mechanical, can be activated and spatially coordinated to induce polarized cell states and directional migration. Physiologically, cells na...

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Bibliografiske detaljer
Udgivet i:J Biomech Eng
Main Authors: Mak, Michael, Spill, Fabian, Kamm, Roger D., Zaman, Muhammad H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Mechanical Engineers 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844084/
https://ncbi.nlm.nih.gov/pubmed/26639083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1115/1.4032188
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