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Single-Cell Migration in Complex Microenvironments: Mechanics and Signaling Dynamics

Cells are highly dynamic and mechanical automata powered by molecular motors that respond to external cues. Intracellular signaling pathways, either chemical or mechanical, can be activated and spatially coordinated to induce polarized cell states and directional migration. Physiologically, cells na...

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Bibliographic Details
Published in:J Biomech Eng
Main Authors: Mak, Michael, Spill, Fabian, Kamm, Roger D., Zaman, Muhammad H.
Format: Artigo
Language:Inglês
Published: American Society of Mechanical Engineers 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844084/
https://ncbi.nlm.nih.gov/pubmed/26639083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1115/1.4032188
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