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Single-Cell Migration in Complex Microenvironments: Mechanics and Signaling Dynamics

Cells are highly dynamic and mechanical automata powered by molecular motors that respond to external cues. Intracellular signaling pathways, either chemical or mechanical, can be activated and spatially coordinated to induce polarized cell states and directional migration. Physiologically, cells na...

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Detalles Bibliográficos
Publicado en:J Biomech Eng
Autores principales: Mak, Michael, Spill, Fabian, Kamm, Roger D., Zaman, Muhammad H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Mechanical Engineers 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844084/
https://ncbi.nlm.nih.gov/pubmed/26639083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1115/1.4032188
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