The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent

BACKGROUND & AIMS: Nonalcoholic fatty liver disease (NAFLD) is a leading cause of liver damage and is characterized by steatosis. Genetic factors increase risk for progressive NAFLD. A genome-wide association study showed that the rs641738 C>T variant in the locus that contains the membrane b...

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Veröffentlicht in:Gastroenterology
Hauptverfasser: Mancina, Rosellina Margherita, Dongiovanni, Paola, Petta, Salvatore, Pingitore, Piero, Meroni, Marica, Rametta, Raffaela, Borén, Jan, Montalcini, Tiziana, Pujia, Arturo, Wiklund, Olov, Hindy, George, Spagnuolo, Rocco, Motta, Benedetta Maria, Pipitone, Rosaria Maria, Craxì, Antonio, Fargion, Silvia, Nobili, Valerio, Käkelä, Pirjo, Kärjä, Vesa, Männistö, Ville, Pihlajamäki, Jussi, Reilly, Dermot F., Castro-Perez, Jose, Kozlitina, Julia, Valenti, Luca, Romeo, Stefano
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844071/
https://ncbi.nlm.nih.gov/pubmed/26850495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2016.01.032
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