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Real-time monitoring of metabolic function in liver-on-chip microdevices tracks the dynamics of mitochondrial dysfunction

Microfluidic organ-on-a-chip technology aims to replace animal toxicity testing, but thus far has demonstrated few advantages over traditional methods. Mitochondrial dysfunction plays a critical role in the development of chemical and pharmaceutical toxicity, as well as pluripotency and disease proc...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Bavli, Danny, Prill, Sebastian, Ezra, Elishai, Levy, Gahl, Cohen, Merav, Vinken, Mathieu, Vanfleteren, Jan, Jaeger, Magnus, Nahmias, Yaakov
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843487/
https://ncbi.nlm.nih.gov/pubmed/27044092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522556113
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