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Challenges and Opportunities in the Design of Liver-on-Chip Microdevices
The liver is the central hub of xenobiotic metabolism and consequently the organ most prone to cosmetic- and drug-induced toxicity. Failure to detect liver toxicity or to assess compound clearance during product development is a major cause of postmarketing product withdrawal, with disastrous clinic...
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| 出版年: | Annu Rev Biomed Eng |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7004816/ https://ncbi.nlm.nih.gov/pubmed/31167098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-bioeng-060418-052305 |
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