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Cellular uptake and anticancer activity of carboxylated gallium corroles

We report derivatives of gallium(III) tris(pentafluorophenyl)corrole, 1 [Ga(tpfc)], with either sulfonic (2) or carboxylic acids (3, 4) as macrocyclic ring substituents: the aminocaproate derivative, 3 [Ga(ACtpfc)], demonstrated high cytotoxic activity against all NCI60 cell lines derived from nine...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Pribisko, Melanie, Palmer, Joshua, Grubbs, Robert H., Gray, Harry B., Termini, John, Lim, Punnajit
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843456/
https://ncbi.nlm.nih.gov/pubmed/27044076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517402113
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