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An In Vitro Enzymatic Assay to Measure Transcription Inhibition by Gallium(III) and H(3) 5,10,15-tris(pentafluorophenyl)corroles

Chemotherapy often involves broad-spectrum cytotoxic agents with many side effects and limited targeting. Corroles are a class of tetrapyrrolic macrocycles that exhibit differential cytostatic and cytotoxic properties in specific cell lines, depending on the identities of the chelated metal and func...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Tang, Grace Y., Pribisko, Melanie A., Henning, Ryan K., Lim, Punnajit, Termini, John, Gray, Harry B., Grubbs, Robert H.
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401371/
https://ncbi.nlm.nih.gov/pubmed/25867444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52355
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