Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors

Pancreatic neuroendocrine tumors (PanNETs) are a type of pancreatic cancer with limited therapeutic options. Consequently, most patients with advanced disease die from tumor progression. Current evidence indicates that a subset of cancer cells is responsible for tumor development, metastasis, and re...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Krampitz, Geoffrey Wayne, George, Benson M., Willingham, Stephen B., Volkmer, Jens-Peter, Weiskopf, Kipp, Jahchan, Nadine, Newman, Aaron M., Sahoo, Debashis, Zemek, Allison J., Yanovsky, Rebecca L., Nguyen, Julia K., Schnorr, Peter J., Mazur, Pawel K., Sage, Julien, Longacre, Teri A., Visser, Brendan C., Poultsides, George A., Norton, Jeffrey A., Weissman, Irving L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843455/
https://ncbi.nlm.nih.gov/pubmed/27035983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600007113
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