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Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay
The cell of origin for prostate cancer remains a subject of debate. Genetically engineered mouse models have demonstrated that both basal and luminal cells can serve as cells of origin for prostate cancer. Using a human prostate regeneration and transformation assay, our group previously demonstrate...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4843433/ https://ncbi.nlm.nih.gov/pubmed/27044116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603645113 |
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