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AB249. 15-oxospiramilactone reverses multidrug resistance in the Human Renal Cell Carcinoma by targeting ABCB1 through Inhibition of Wnt/β-catenin signaling
BACKGROUND: Multidrug resistance (MDR) is the main barrier to the success of chemotherapy for Human Renal Cell Carcinoma. P-glycoprotein ABCB1 plays a major role in MDR of malignant cells and is regulated by various transcription factors, including Wnt/β-catenin /TCF4. We previously reported 15-oxos...
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| Publié dans: | Transl Androl Urol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
AME Publishing Company
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4842754/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau.2016.s249 |
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