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AB173. TR4 nuclear receptor increases prostate cancer invasion via decreasing the miR-373-3p expression to alter TGFβR2/p-Smad3 signals

OBJECTIVE: Testicular nuclear receptor 4 (TR4) is a member of the nuclear receptor superfamily, which may play key roles to influence the metabolic diseases and prostate tumorigenesis. The purpose of our study is to elucidate the mechanisms how TR4 influences the prostate cancer (PCa) metastasis. ME...

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Veröffentlicht in:Transl Androl Urol
Hauptverfasser: Yang, Guosheng, Qiu, Xiaofo
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842613/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau.2016.s173
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