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The Effects of Imatinib Mesylate on Cellular Viability, Platelet Derived Growth Factor and Stem Cell Factor in Mouse Testicular Normal Leydig Cells

BACKGROUND: Growth factors play an essential role in the development of tumor and normal cells like testicular leydig cells. Treatment of cancer with anti-cancer agents like imatinib mesylate may interfere with normal leydig cell activity, growth and fertility through failure in growth factors’ prod...

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Detalhes bibliográficos
Publicado no:J Reprod Infertil
Main Authors: Kheradmand, Fatemeh, Hashemnia, Seyyed Mohammad Reza, Valizadeh, Nasim, Roshan-Milani, Shiva
Formato: Artigo
Idioma:Inglês
Publicado em: Avicenna Research Institute 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842238/
https://ncbi.nlm.nih.gov/pubmed/27141462
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