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A unified set-based test with adaptive filtering for gene-environment interaction analyses

In genome-wide gene-environment interaction (GxE) studies, a common strategy to improve power is to first conduct a filtering test and retain only the SNPs that pass the filtering in the subsequent GxE analyses. Inspired by two-stage tests and gene-based tests in GxE analysis, we consider the genera...

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Foilsithe in:Biometrics
Main Authors: Liu, Qianying, Chen, Lin S., Nicolae, Dan L., Pierce, Brandon L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842175/
https://ncbi.nlm.nih.gov/pubmed/26496228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12428
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