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Two-stage testing procedures with independent filtering for genome-wide gene-environment interaction

Several two-stage multiple testing procedures have been proposed to detect gene-environment interaction in genome-wide association studies. In this article, we elucidate general conditions that are required for validity and power of these procedures, and we propose extensions of two-stage procedures...

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Detalhes bibliográficos
Main Authors: Dai, James Y., Kooperberg, Charles, Leblanc, Michael, Prentice, Ross L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629859/
https://ncbi.nlm.nih.gov/pubmed/23843674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biomet/ass044
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