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Involvement of the Extrinsic and Intrinsic Pathways in Ultraviolet B-Induced Apoptosis of Corneal Epithelial Cells

The goal of this study was to elucidate the pathway by which UVB initiates efflux of K(+) and subsequently apoptosis in human corneal limbal epithelial (HCLE) cells. The initial focus of the study was on the extrinsic pathway involving Fas. HCLE cells transfected with Fas siRNA were exposed to 80–15...

詳細記述

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書誌詳細
出版年:Exp Eye Res
主要な著者: Ubels, John L., Glupker, Courtney D., Schotanus, Mark P., Haarsma, Loren D.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842139/
https://ncbi.nlm.nih.gov/pubmed/26559338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.11.003
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