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A simple, rapid, high-fidelity and cost-effective PCR-based two-step DNA synthesis method for long gene sequences

Chemical synthesis of DNA sequences provides a powerful tool for modifying genes and for studying gene function, structure and expression. Here, we report a simple, high-fidelity and cost-effective PCR-based two-step DNA synthesis (PTDS) method for synthesis of long segments of DNA. The method invol...

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Detalhes bibliográficos
Main Authors: Xiong, Ai-Sheng, Yao, Quan-Hong, Peng, Ri-He, Li, Xian, Fan, Hui-Qin, Cheng, Zong-Ming, Li, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC484193/
https://ncbi.nlm.nih.gov/pubmed/15240836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh094
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