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Reverse gyrase has heat-protective DNA chaperone activity independent of supercoiling
Hyperthermophilic organisms must protect their constituent macromolecules from heat-induced degradation. A general mechanism for thermoprotection of DNA in active cells is unknown. We show that reverse gyrase, the only protein that is both specific and common to all hyperthermophiles, reduces the ra...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC484171/ https://ncbi.nlm.nih.gov/pubmed/15247343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh683 |
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